{"id":170,"date":"2023-01-27T14:26:13","date_gmt":"2023-01-27T14:26:13","guid":{"rendered":"https:\/\/szte-genetika.hu\/?page_id=170"},"modified":"2026-03-18T14:45:21","modified_gmt":"2026-03-18T14:45:21","slug":"kronogenetikai-csoport","status":"publish","type":"page","link":"https:\/\/szte-genetika.hu\/en\/kronogenetikai-csoport\/","title":{"rendered":"Chronogenetics Research Group"},"content":{"rendered":"<p>[et_pb_section fb_built=&#8221;1&#8243; _builder_version=&#8221;4.19.4&#8243; _module_preset=&#8221;default&#8221; background_enable_color=&#8221;off&#8221; use_background_color_gradient=&#8221;on&#8221; background_color_gradient_stops=&#8221;rgba(0,141,180,0.35) 1%|rgba(0,81,103,0.65) 100%&#8221; background_image=&#8221;https:\/\/szte-genetika.hu\/wp-content\/uploads\/2023\/01\/kronogenetika.webp&#8221; background_size=&#8221;custom&#8221; background_image_width=&#8221;42%&#8221; background_position=&#8221;center_right&#8221; background_horizontal_offset=&#8221;0%&#8221; background_blend=&#8221;overlay&#8221; background_enable_mask_style=&#8221;on&#8221; background_mask_style=&#8221;diagonal-bars&#8221; background_mask_color=&#8221;#005167&#8243; background_mask_size=&#8221;cover&#8221; top_divider_color=&#8221;#007FA9&#8243; top_divider_height=&#8221;50px&#8221; background_last_edited=&#8221;on|phone&#8221; background_image_width_tablet=&#8221;45%&#8221; background_image_width_phone=&#8221;80%&#8221; global_colors_info=&#8221;{}&#8221;][et_pb_row _builder_version=&#8221;4.19.4&#8243; _module_preset=&#8221;default&#8221; custom_padding=&#8221;||0px||false|false&#8221; global_colors_info=&#8221;{}&#8221;][et_pb_column type=&#8221;4_4&#8243; _builder_version=&#8221;4.19.4&#8243; _module_preset=&#8221;default&#8221; global_colors_info=&#8221;{}&#8221;][et_pb_text _builder_version=&#8221;4.19.4&#8243; _module_preset=&#8221;default&#8221; header_font=&#8221;Sofia Sans medium|500|||||||&#8221; header_text_color=&#8221;#F4F4F4&#8243; header_font_size=&#8221;40px&#8221; width_tablet=&#8221;70%&#8221; width_phone=&#8221;100%&#8221; width_last_edited=&#8221;on|desktop&#8221; global_colors_info=&#8221;{}&#8221;]<\/p>\n<h1>Kronogenetikai kutat\u00f3csoport<\/h1>\n<p>[\/et_pb_text][\/et_pb_column][\/et_pb_row][et_pb_row _builder_version=&#8221;4.19.4&#8243; _module_preset=&#8221;default&#8221; global_colors_info=&#8221;{}&#8221;][et_pb_column type=&#8221;4_4&#8243; _builder_version=&#8221;4.19.4&#8243; _module_preset=&#8221;default&#8221; global_colors_info=&#8221;{}&#8221;][et_pb_divider color=&#8221;#8BCE33&#8243; divider_weight=&#8221;5px&#8221; _builder_version=&#8221;4.19.4&#8243; _module_preset=&#8221;default&#8221; width=&#8221;20%&#8221; width_tablet=&#8221;40%&#8221; width_phone=&#8221;40%&#8221; width_last_edited=&#8221;on|phone&#8221; global_colors_info=&#8221;{}&#8221;][\/et_pb_divider][\/et_pb_column][\/et_pb_row][\/et_pb_section][et_pb_section fb_built=&#8221;1&#8243; _builder_version=&#8221;4.19.4&#8243; _module_preset=&#8221;default&#8221; background_color=&#8221;#F4F4F4&#8243; custom_padding=&#8221;||||false|false&#8221; bottom_divider_color=&#8221;#007FA9&#8243; bottom_divider_height=&#8221;50px&#8221; global_colors_info=&#8221;{}&#8221;][et_pb_row column_structure=&#8221;3_5,2_5&#8243; _builder_version=&#8221;4.19.4&#8243; _module_preset=&#8221;default&#8221; custom_padding=&#8221;0px||0px||false|false&#8221; global_colors_info=&#8221;{}&#8221;][et_pb_column type=&#8221;3_5&#8243; _builder_version=&#8221;4.19.4&#8243; _module_preset=&#8221;default&#8221; global_colors_info=&#8221;{}&#8221;][et_pb_text _builder_version=&#8221;4.19.4&#8243; _module_preset=&#8221;default&#8221; text_font=&#8221;||||||||&#8221; link_font=&#8221;|600|||on|||#00C79C|solid&#8221; link_text_color=&#8221;#007FA9&#8243; text_orientation=&#8221;justified&#8221; width_tablet=&#8221;100%&#8221; width_phone=&#8221;100%&#8221; width_last_edited=&#8221;off|desktop&#8221; custom_margin=&#8221;||||false|false&#8221; custom_margin_tablet=&#8221;0px||||false|false&#8221; custom_margin_phone=&#8221;0px||||false|false&#8221; custom_margin_last_edited=&#8221;on|desktop&#8221; text_orientation_tablet=&#8221;justified&#8221; text_orientation_phone=&#8221;left&#8221; text_orientation_last_edited=&#8221;on|phone&#8221; global_colors_info=&#8221;{}&#8221; link_text_color__hover_enabled=&#8221;on|desktop&#8221; link_text_color__hover=&#8221;#00C79C&#8221;]<\/p>\n<h2>Kutat\u00e1si t\u00e9ma<\/h2>\n<p>Az eukari\u00f3ta cirkadi\u00e1n \u00f3r\u00e1k val\u00f3j\u00e1ban oszcill\u00e1l\u00f3 g\u00e9nh\u00e1l\u00f3zatok, amelyekben az els\u0151dleges ritmus az \u00f3rag\u00e9nek transzkripci\u00f3j\u00e1nak szintj\u00e9n alakul ki, majd t\u00f6bb kieg\u00e9sz\u00edt\u0151 szab\u00e1lyoz\u00f3 mechanizmus k\u00f6zrem\u0171k\u00f6d\u00e9s\u00e9vel \u00e1ll\u00edt\u00f3dik kb. 24 \u00f3r\u00e1s peri\u00f3dusra (<strong>1. \u00e1bra<\/strong>). Ez az alap-oszill\u00e1ci\u00f3, mint egyfajta karmester, sz\u00e1mos \u00e9letfolyamat megjelen\u00e9s\u00e9t szab\u00e1lyozza olyan m\u00f3don, hogy azok az arra legmegfelel\u0151bb napszakban t\u00f6rt\u00e9njenek. Bel\u00e1that\u00f3, hogy az \u00f3ra biol\u00f3giai szerep\u00e9t akkor tudja bet\u00f6lteni, ha a nappalok \u00e9s \u00e9jszak\u00e1k v\u00e1ltakoz\u00e1s\u00e1val \u00f6sszhangban m\u0171k\u00f6dik, \u00e9s a peri\u00f3dusa k\u00f6zel\u00edti a F\u00f6ld forg\u00e1s\u00e1b\u00f3l ad\u00f3d\u00f3 24 \u00f3r\u00e1t.<\/p>\n<p>A modern n\u00f6v\u00e9nybiol\u00f3gia modelln\u00f6v\u00e9ny\u00e9n (<em>Arabidopsis thaliana<\/em>, l\u00fadf\u0171) v\u00e9gzett kutat\u00e1saink sor\u00e1n azonos\u00edtottuk azokat a f\u00e9ny\u00e9rz\u00e9kel\u0151 feh\u00e9rj\u00e9ket (fotoreceptorok), amelyek a k\u00f6rnyezetb\u0151l sz\u00e1rmaz\u00f3 szinkroniz\u00e1l\u00f3 f\u00e9nyt \u00e9rz\u00e9kelik, \u00e9s le\u00edrtuk azokat a transzkripci\u00f3s faktorokat, amelyek e fotoreceptorokt\u00f3l sz\u00e1rmaz\u00f3 jeleket k\u00f6zvetlen\u00fcl az \u00f3rag\u00e9nek kifejez\u0151d\u00e9s\u00e9nek szintj\u00e9re tov\u00e1bb\u00edtj\u00e1k, vagyis megteremtik az \u00f6sszhangot az \u00f3ra \u00e9s a k\u00f6rnyezet k\u00f6z\u00f6tt.<\/p>\n<p>Egy sikeres mut\u00e1ns sz\u0171r\u00e9s sor\u00e1n azonos\u00edtottunk k\u00e9t olyan mut\u00e1ci\u00f3t k\u00e9t g\u00e9nben, amelyek eddig ismeretlen peri\u00f3dust szab\u00e1lyoz\u00f3 mechanizmusok l\u00e9t\u00e9re utalnak. Az els\u0151 g\u00e9n egy ubikvitin prote\u00e1zt (UBP12) k\u00f3dol, amely ubikvitint t\u00e1vol\u00edt el feh\u00e9rj\u00e9kr\u0151l, t\u00f6bbek k\u00f6z\u00f6tt \u00f3rafeh\u00e9rj\u00e9kr\u0151l is. Az \u00e1ltalunk azonos\u00edtott mut\u00e1ci\u00f3 vizsg\u00e1lata arra utal, hogy a prote\u00e1z \u00f3rafeh\u00e9rj\u00e9kre gyakorolt hat\u00e1s\u00e1t a prote\u00e1z foszforil\u00e1lts\u00e1gi \u00e1llapota hat\u00e1rozza meg. Ezt a hipot\u00e9zist olyan mesters\u00e9ges v\u00e1ltozatok el\u0151\u00e1ll\u00edt\u00e1s\u00e1val \u00e9s vizsg\u00e1lat\u00e1val tesztelj\u00fck, amelyek foszforil\u00e1lt vagy nem foszforil\u00e1lt \u00e1llapotban r\u00f6gz\u00fcltek. Az UBP12 homol\u00f3gjai megtal\u00e1lhat\u00f3ak \u00e1llati rendszerekben is, ahol szint\u00e9n r\u00e9szt vesznek az \u00f3ra szab\u00e1lyoz\u00e1s\u00e1ban. Ez\u00e9rt terveink k\u00f6z\u00f6tt szerepel annak tesztel\u00e9se is, hogy a foszforil\u00e1ci\u00f3 n\u00f6v\u00e9nyekben \u00e9s \u00e1llatokban is hasonl\u00f3an szab\u00e1lyozza-e az ubikvitin prote\u00e1z cirkadi\u00e1n funkci\u00f3j\u00e1t.<\/p>\n<p>[\/et_pb_text][\/et_pb_column][et_pb_column type=&#8221;2_5&#8243; _builder_version=&#8221;4.19.4&#8243; _module_preset=&#8221;default&#8221; global_colors_info=&#8221;{}&#8221;][et_pb_image src=&#8221;https:\/\/szte-genetika.hu\/wp-content\/uploads\/2023\/01\/kronogenetika_1_KOZMA.webp&#8221; alt=&#8221;kronogenetika biol\u00f3giai \u00f3ra szab\u00e1lyoz\u00e1sa&#8221; title_text=&#8221;n\u00f6v\u00e9nyi cirkadi\u00e1n \u00f3ra&#8221; _builder_version=&#8221;4.19.4&#8243; _module_preset=&#8221;default&#8221; box_shadow_style=&#8221;preset4&#8243; box_shadow_horizontal=&#8221;20px&#8221; box_shadow_vertical=&#8221;20px&#8221; box_shadow_color=&#8221;#006E8C&#8221; global_colors_info=&#8221;{}&#8221;][\/et_pb_image][et_pb_text _builder_version=&#8221;4.19.4&#8243; _module_preset=&#8221;default&#8221; text_font=&#8221;||||||||&#8221; link_font=&#8221;|600|||on|||#00C79C|solid&#8221; link_text_color=&#8221;#007FA9&#8243; text_orientation=&#8221;justified&#8221; text_orientation_tablet=&#8221;justified&#8221; text_orientation_phone=&#8221;left&#8221; text_orientation_last_edited=&#8221;on|phone&#8221; global_colors_info=&#8221;{}&#8221; link_text_color__hover=&#8221;#00C79C&#8221; link_text_color__hover_enabled=&#8221;on|desktop&#8221;]<\/p>\n<p><strong>1. \u00e1bra A n\u00f6v\u00e9nyi cirkadi\u00e1n \u00f3ra modellje<br \/><\/strong>Az \u00f3rag\u00e9neket n\u00e9gysz\u00f6gek, a feh\u00e9rj\u00e9ket ellipszisek jelzik. A pozit\u00edv vagy negat\u00edv hat\u00e1sokat z\u00f6ld vagy piros vonalakkal jel\u00f6lt\u00fck. A vill\u00e1m szimb\u00f3lumok f\u00e9nyszab\u00e1lyozott l\u00e9p\u00e9sekre utalnak (s\u00e1rga: aktiv\u00e1l\u00e1s, fekete: g\u00e1tl\u00e1s). A n\u00f6v\u00e9nyi \u00f3r\u00e1t h\u00e1rom, egym\u00e1ssal \u00f6sszekapcsolt szab\u00e1lyoz\u00f3 hurok \u00e9p\u00edti fel, amelyek egy\u00fcttesen hozz\u00e1k l\u00e9tre a kb. 24 \u00f3r\u00e1s alap-oszcill\u00e1ci\u00f3t. A rendszer, b\u00e1r er\u0151sen megv\u00e1ltozott peri\u00f3dussal \u00e9s amplit\u00fad\u00f3val, de k\u00e9pes \u00f6nfenntart\u00f3 oszcill\u00e1ci\u00f3ra akkor is, ha az egyik hurok m\u0171k\u00f6d\u00e9se megsz\u0171nik (pl. az adott \u00f3rag\u00e9n mut\u00e1ci\u00f3ja miatt).<\/p>\n<p>[\/et_pb_text][\/et_pb_column][\/et_pb_row][et_pb_row column_structure=&#8221;3_5,2_5&#8243; _builder_version=&#8221;4.19.4&#8243; _module_preset=&#8221;default&#8221; custom_padding=&#8221;||||false|false&#8221; global_colors_info=&#8221;{}&#8221;][et_pb_column type=&#8221;3_5&#8243; _builder_version=&#8221;4.19.4&#8243; _module_preset=&#8221;default&#8221; global_colors_info=&#8221;{}&#8221;][et_pb_text _builder_version=&#8221;4.19.4&#8243; _module_preset=&#8221;default&#8221; text_font=&#8221;||||||||&#8221; link_font=&#8221;|600|||on|||#00C79C|solid&#8221; link_text_color=&#8221;#007FA9&#8243; text_orientation=&#8221;justified&#8221; width_tablet=&#8221;100%&#8221; width_phone=&#8221;100%&#8221; width_last_edited=&#8221;off|desktop&#8221; custom_margin=&#8221;||||false|false&#8221; custom_margin_tablet=&#8221;0px||||false|false&#8221; custom_margin_phone=&#8221;0px||||false|false&#8221; custom_margin_last_edited=&#8221;on|desktop&#8221; text_orientation_tablet=&#8221;justified&#8221; text_orientation_phone=&#8221;left&#8221; text_orientation_last_edited=&#8221;on|phone&#8221; global_colors_info=&#8221;{}&#8221; link_text_color__hover_enabled=&#8221;on|desktop&#8221; link_text_color__hover=&#8221;#00C79C&#8221;]<\/p>\n<p>A m\u00e1sik feh\u00e9rje egy \u00e9rdekes szerkezet\u0171 protein, amely egy \u00e1ltal\u00e1nos k\u00f6lcs\u00f6nhat\u00f3 felsz\u00ednt reprezent\u00e1l\u00f3 mot\u00edvumot tartalmaz az N-termin\u00e1lis v\u00e9gen, m\u00edg a megtal\u00e1lt mut\u00e1ci\u00f3 egy egyel\u0151re ismeretlen funkci\u00f3j\u00fa dom\u00e9nt azonos\u00edt a C-termin\u00e1lison. C\u00e9lunk ennek a funkci\u00f3nak a min\u00e9l r\u00e9szletesebb felt\u00e1r\u00e1sa a feh\u00e9rje \u00e1ltal k\u00f6zvetlen\u00fcl vagy k\u00f6zvetve szab\u00e1lyozott\/\u00e9rintett \u00f3rag\u00e9nek \u00e9s egy\u00e9b g\u00e9nek meghat\u00e1roz\u00e1sa, \u00e9s a regul\u00e1ci\u00f3 mechanizmus\u00e1nak le\u00edr\u00e1sa \u00e1ltal.<\/p>\n<p>Folyamatosan fejlesztett kutat\u00e1si eszk\u00f6zeink \u00e9s m\u00f3dszereink a modern molekul\u00e1ris biol\u00f3gia sz\u00e1mos ter\u00fclet\u00e9t lefedik (g\u00e9nkifejez\u0151d\u00e9s meghat\u00e1roz\u00e1sa, genetikai t\u00e9rk\u00e9pez\u00e9s, g\u00e9n izol\u00e1l\u00e1s\/m\u00f3dos\u00edt\u00e1s, cirkadi\u00e1n-szab\u00e1lyozott lumineszcens riporterek alkalmaz\u00e1sa transzgenikus \u00e9l\u0151l\u00e9nyekben)(<strong>2. \u00e1bra<\/strong>), \u00edgy az \u00e1ltaluk szerzett tud\u00e1s \u00e9s tapasztalat nagyon sokf\u00e9le \u00e9s egy\u00e9b modell-szervezeteket c\u00e9lz\u00f3 kutat\u00e1si t\u00e9ma m\u0171vel\u00e9sekor is kamatoztathat\u00f3.<\/p>\n<p>A cirkadi\u00e1n \u00f3ra seg\u00edti a n\u00f6v\u00e9nyek optim\u00e1lis n\u00f6veked\u00e9s\u00e9t az\u00e1ltal, hogy alapvet\u0151 folyamatokat elrendez a nap sor\u00e1n. Bel\u00e1that\u00f3, hogy jelenleg zajl\u00f3 dr\u00e1mai m\u00e9rt\u00e9k\u0171 \u00e9s sebess\u00e9g\u0171 kl\u00edmav\u00e1ltoz\u00e1s olyan \u00faj napi elrendez\u00e9s\u00e9t ig\u00e9nyeln\u00e9 ezeknek a folyamatoknak, amelyet a szelekci\u00f3 alapj\u00e1n v\u00e1ltoz\u00f3 \u00f3ra nem k\u00e9pes k\u00f6vetni. Ilyen k\u00f6r\u00fclm\u00e9nyek k\u00f6z\u00f6tt, az \u00f3ra m\u0171k\u00f6d\u00e9s\u00e9nek \u00e9s a k\u00f6rnyezettel val\u00f3 kapcsolat\u00e1nak r\u00e9szletes ismerete fontos \u00e9s \u00e9rt\u00e9kes eszk\u00f6z lehet az agr\u00e1rium innov\u00e1ci\u00f3ja szempontj\u00e1b\u00f3l.<\/p>\n<p>[\/et_pb_text][\/et_pb_column][et_pb_column type=&#8221;2_5&#8243; _builder_version=&#8221;4.19.4&#8243; _module_preset=&#8221;default&#8221; global_colors_info=&#8221;{}&#8221;][et_pb_image src=&#8221;https:\/\/szte-genetika.hu\/wp-content\/uploads\/2023\/01\/kronogenetika.webp&#8221; alt=&#8221;kronogenetika&#8221; title_text=&#8221;kronogenetika&#8221; _builder_version=&#8221;4.19.4&#8243; _module_preset=&#8221;default&#8221; box_shadow_style=&#8221;preset4&#8243; box_shadow_horizontal=&#8221;20px&#8221; box_shadow_vertical=&#8221;20px&#8221; box_shadow_color=&#8221;#006E8C&#8221; global_colors_info=&#8221;{}&#8221;][\/et_pb_image][et_pb_text _builder_version=&#8221;4.19.4&#8243; _module_preset=&#8221;default&#8221; text_font=&#8221;||||||||&#8221; link_font=&#8221;|600|||on|||#00C79C|solid&#8221; link_text_color=&#8221;#007FA9&#8243; text_orientation=&#8221;justified&#8221; text_orientation_tablet=&#8221;justified&#8221; text_orientation_phone=&#8221;left&#8221; text_orientation_last_edited=&#8221;on|phone&#8221; global_colors_info=&#8221;{}&#8221; link_text_color__hover=&#8221;#00C79C&#8221; link_text_color__hover_enabled=&#8221;on|desktop&#8221;]<\/p>\n<p><strong>1. \u00e1bra Egy \u00f3raszab\u00e1lyozott promoter:lucifer\u00e1z g\u00e9nkonstrukci\u00f3 ritmikus aktivit\u00e1sa transzgenikus n\u00f6v\u00e9nyekben<br \/><\/strong>Az \u00e1bra fels\u0151 r\u00e9sz\u00e9n ugyanazon n\u00f6v\u00e9nycsoportr\u00f3l k\u00e9sz\u00edtett digit\u00e1lis felv\u00e9tel-sorozat l\u00e1that\u00f3. A felv\u00e9telek id\u0151pontj\u00e1t (\u00f3ra) a panel felett, a napj\u00e1t pedig bal oldalt jel\u00f6lt\u00fck. Az \u00e1bra als\u00f3 r\u00e9sz\u00e9n a k\u00e9pek feldolgoz\u00e1sa ut\u00e1n kapott relat\u00edv lucifer\u00e1z aktivit\u00e1s \u00e9rt\u00e9keket \u00e1br\u00e1zoltuk az id\u0151 f\u00fcggv\u00e9ny\u00e9ben. A f\u00e9nyviszonyokat az id\u0151 tengely felett elhelyezett feh\u00e9r (f\u00e9ny) \u00e9s fekete (s\u00f6t\u00e9t) s\u00e1vok jelzik. <\/p>\n<p>[\/et_pb_text][\/et_pb_column][\/et_pb_row][et_pb_row _builder_version=&#8221;4.25.0&#8243; _module_preset=&#8221;default&#8221; global_colors_info=&#8221;{}&#8221;][et_pb_column type=&#8221;4_4&#8243; _builder_version=&#8221;4.25.0&#8243; _module_preset=&#8221;default&#8221; global_colors_info=&#8221;{}&#8221;][et_pb_toggle title=&#8221;Publik\u00e1ci\u00f3k&#8221; open_toggle_text_color=&#8221;#006E8C&#8221; open_toggle_background_color=&#8221;RGBA(255,255,255,0)&#8221; closed_toggle_background_color=&#8221;#006E8C&#8221; icon_color=&#8221;#8BCE33&#8243; toggle_icon=&#8221;&#xe044;||divi||400&#8243; use_icon_font_size=&#8221;on&#8221; icon_font_size=&#8221;25px&#8221; open_icon_color=&#8221;#8BCE33&#8243; open_toggle_icon=&#8221;&#xe043;||divi||400&#8243; open_use_icon_font_size=&#8221;on&#8221; open_icon_font_size=&#8221;25px&#8221; closed_toggle_background_color_tablet=&#8221;&#8221; closed_toggle_background_color_phone=&#8221;#EAEAEA&#8221; closed_toggle_background_color_last_edited=&#8221;on|phone&#8221; _builder_version=&#8221;4.25.0&#8243; _module_preset=&#8221;default&#8221; title_text_color=&#8221;#EAEAEA&#8221; title_level=&#8221;h2&#8243; body_link_font=&#8221;|600|||on|||#8BCE33|&#8221; body_link_text_color=&#8221;#008DB4&#8243; width=&#8221;80%&#8221; width_tablet=&#8221;100%&#8221; width_phone=&#8221;100%&#8221; width_last_edited=&#8221;on|phone&#8221; max_width_tablet=&#8221;100%&#8221; max_width_phone=&#8221;100%&#8221; max_width_last_edited=&#8221;on|desktop&#8221; custom_margin=&#8221;|||-20px|false|false&#8221; custom_margin_tablet=&#8221;|||0px|false|false&#8221; custom_margin_phone=&#8221;|||0px|false|false&#8221; custom_margin_last_edited=&#8221;on|phone&#8221; custom_padding_tablet=&#8221;&#8221; custom_padding_phone=&#8221;|0px||0px|false|false&#8221; custom_padding_last_edited=&#8221;on|phone&#8221; hover_enabled=&#8221;0&#8243; title_text_color_tablet=&#8221;&#8221; title_text_color_phone=&#8221;#008DB4&#8243; title_text_color_last_edited=&#8221;on|phone&#8221; border_width_all=&#8221;0px&#8221; global_colors_info=&#8221;{}&#8221; body_link_text_color__hover_enabled=&#8221;on|desktop&#8221; body_link_text_color__hover=&#8221;#6EC200&#8243; sticky_enabled=&#8221;0&#8243;]<\/p>\n<p>Merai Zsuzsanna, Xu Fei, Hajdu Anita, Kozma-Bognar Laszlo, Dolan Liam (2025).<strong> Phytochrome A is required for light-inhibited germination of Aethionema arabicum seed. <\/strong> <em>NEW PHYTOLOGIST<\/em> <span><a href=\"https:\/\/doi.org\/10.1111\/nph.70344\" target=\"_blank\" rel=\"noopener\"> Elolvasom<\/a><\/span> <\/p>\n<p>Hajdu Anita, Ny\u00e1ri D\u00f3ra Vivien, \u00c1d\u00e1m \u00c9va, Kim Yeon Jeong, Somers David E., Silhavy D\u00e1niel, Nagy Ferenc, Kozma-Bogn\u00e1r L\u00e1szl\u00f3 (2024).<strong> Forward genetic approach identifies a phylogenetically conserved serine residue critical for the catalytic activity of UBIQUITIN-SPECIFIC PROTEASE 12 in Arabidopsis.<\/strong> <em>SCIENTIFIC REPORTS<\/em> <span><a href=\"https:\/\/doi.org\/10.1038\/s41598-024-77232-w\" target=\"_blank\" rel=\"noopener\"> Elolvasom<\/a><\/span> <\/p>\n<p>Hajdu Anita, Ny\u00e1ri D\u00f3ra, Terecskei Kata, Gyula P\u00e9ter, \u00c1d\u00e1m \u00c9va, Dobos Orsolya, M\u00e9rai Zsuzsanna, Kozma-Bogn\u00e1r L\u00e1szl\u00f3 (2024).<strong> LIP1 Regulates the Plant Circadian Oscillator by Modulating the Function of the Clock Component GIGANTEA.<\/strong> <em>CELLS<\/em> <span><a href=\"https:\/\/doi.org\/10.3390\/cells13171503\" target=\"_blank\" rel=\"noopener\"> Elolvasom<\/a><\/span> <\/p>\n<p>Peter Csaba, Adam Eva, Klose Cornelia, Grezal Gabor, Hajdu Anita, Steinbach Gabor, Kozma-Bognar Laszlo, Silhavy Daniel, Nagy Ferenc, Viczian Andras (2024).<strong> Phytochrome C and Low Temperature Promote the Protein Accumulation and Red-Light Signaling of Phytochrome D.<\/strong> <em>PLANT AND CELL PHYSIOLOGY<\/em> <span><a href=\"https:\/\/doi.org\/10.1093\/pcp\/pcae089\" target=\"_blank\" rel=\"noopener\"> Elolvasom<\/a><\/span> <\/p>\n<p>Gombos Magdolna, Hapek N\u00f3ra, Kozma-Bogn\u00e1r L\u00e1szl\u00f3, Grezal G\u00e1bor, Zombori Zolt\u00e1n, Kiss Edina, Gy\u00f6rgyey J\u00e1nos (2023).<strong> Limited water stress modulates expression of circadian clock genes in Brachypodium distachyon roots,<\/strong><em> SCIENTIFIC REPORTS<\/em> <span><a href=\"https:\/\/doi.org\/10.1038\/s41598-022-27287-4\" target=\"_blank\" rel=\"noopener\"> Elolvasom<\/a><\/span> <\/p>\n<p>Bernula P\u00e9ter, Pettk\u00f3-Szandtner Alad\u00e1r, Hajdu Anita, Kozma-Bogn\u00e1r L\u00e1szl\u00f3, Josse Eve-Marie, \u00c1d\u00e1m \u00c9va, Nagy Ferenc, Viczi\u00e1n Andr\u00e1s (2021).<strong> SUMOylation of PHYTOCHROME INTERACTING FACTOR 3 promotes photomorphogenesis in Arabidopsis thaliana.<\/strong> <em>NEW PHYTOLOGIST<\/em> <span><a href=\"https:\/\/doi.org\/10.1111\/nph.17013\" target=\"_blank\" rel=\"noopener\"> Elolvasom<\/a><\/span> <\/p>\n<p>Kovacs Hajnalka, Aleksza David, Baba Abu Imran, Hajdu Anita, Kiraly Anna Maria, Zsigmond Laura, Toth Szilvia Z., Kozma-Bognar Laszlo, Szabados Laszlo (2019).<strong> Light Control of Salt-Induced Proline Accumulation Is Mediated by ELONGATED HYPOCOTYL 5 in Arabidopsis.<\/strong> <em>FRONTIERS IN PLANT SCIENCE<\/em> <span><a href=\"https:\/\/doi.org\/10.3389\/fpls.2019.01584\" target=\"_blank\" rel=\"noopener\"> Elolvasom<\/a><\/span> <\/p>\n<p>Gould PD, Domijian M, Greenwood M, Tokuda IT, Rees H, Kozma-Bognar L, Hall AJW, Locke JCW (2018). <strong>Coordination of robust single cell rhythms in the Arabidopsis circadian clock via spatial waves of gene expression.<\/strong> <em>ELIFE<\/em> <span><a href=\"https:\/\/doi.org\/10.7554\/eLife.31700\" target=\"_blank\" rel=\"noopener\"> Elolvasom<\/a><\/span> <\/p>\n<p>Hajdu Anita, Dobos Orsolya, Domijan Mirela, Balint Balazs, Nagy Istvan, Nagy Ferenc, Kozma-Bognar Laszlo (2018).<strong> ELONGATED HYPOCOTYL 5 mediates blue light signalling to the Arabidopsis circadian clock.<\/strong> <em>PLANT JOURNAL<\/em> <span><a href=\"https:\/\/doi.org\/10.1111\/tpj.14106\" target=\"_blank\" rel=\"noopener\"> Elolvasom<\/a><\/span> <\/p>\n<p>[\/et_pb_toggle][\/et_pb_column][\/et_pb_row][et_pb_row _builder_version=&#8221;4.19.4&#8243; _module_preset=&#8221;default&#8221; custom_padding=&#8221;||||false|false&#8221; global_colors_info=&#8221;{}&#8221;][et_pb_column type=&#8221;4_4&#8243; _builder_version=&#8221;4.19.4&#8243; _module_preset=&#8221;default&#8221; global_colors_info=&#8221;{}&#8221;][et_pb_text _builder_version=&#8221;4.19.4&#8243; _module_preset=&#8221;default&#8221; text_font=&#8221;||||||||&#8221; text_text_color=&#8221;#3D3D3D&#8221; link_font=&#8221;|600|||on|||#00C79C|solid&#8221; link_text_color=&#8221;#007FA9&#8243; text_orientation=&#8221;justified&#8221; width=&#8221;70%&#8221; width_tablet=&#8221;100%&#8221; width_phone=&#8221;100%&#8221; width_last_edited=&#8221;on|tablet&#8221; custom_margin=&#8221;||||false|false&#8221; custom_margin_tablet=&#8221;0px||||false|false&#8221; custom_margin_phone=&#8221;0px||||false|false&#8221; custom_margin_last_edited=&#8221;off|desktop&#8221; text_orientation_tablet=&#8221;justified&#8221; text_orientation_phone=&#8221;left&#8221; text_orientation_last_edited=&#8221;on|phone&#8221; global_colors_info=&#8221;{}&#8221; link_text_color__hover_enabled=&#8221;on|desktop&#8221; link_text_color__hover=&#8221;#00C79C&#8221;]<\/p>\n<h2>A kronogenetikai kutat\u00f3csoport munkat\u00e1rsai:<\/h2>\n<p>[\/et_pb_text][\/et_pb_column][\/et_pb_row][et_pb_row column_structure=&#8221;1_3,1_3,1_3&#8243; use_custom_gutter=&#8221;on&#8221; gutter_width=&#8221;2&#8243; make_equal=&#8221;on&#8221; _builder_version=&#8221;4.19.5&#8243; _module_preset=&#8221;default&#8221; custom_padding=&#8221;0px||||false|false&#8221; global_colors_info=&#8221;{}&#8221;][et_pb_column type=&#8221;1_3&#8243; _builder_version=&#8221;4.19.5&#8243; _module_preset=&#8221;default&#8221; box_shadow_style=&#8221;preset1&#8243; box_shadow_blur=&#8221;10px&#8221; global_colors_info=&#8221;{}&#8221;][et_pb_image src=&#8221;https:\/\/szte-genetika.hu\/wp-content\/uploads\/2023\/02\/Kozma-BognarLaszlo.webp&#8221; alt=&#8221;Dr. Kozma-Bogn\u00e1r L\u00e1szl\u00f3&#8221; title_text=&#8221;Dr. Kozma-Bogn\u00e1r L\u00e1szl\u00f3&#8221; align_tablet=&#8221;&#8221; align_phone=&#8221;center&#8221; align_last_edited=&#8221;on|phone&#8221; _builder_version=&#8221;4.19.5&#8243; _module_preset=&#8221;default&#8221; width=&#8221;100%&#8221; width_tablet=&#8221;100%&#8221; width_phone=&#8221;100%&#8221; width_last_edited=&#8221;on|phone&#8221; custom_margin=&#8221;||10px||false|false&#8221; custom_padding=&#8221;20px|20px||20px|false|false&#8221; custom_padding_last_edited=&#8221;off|desktop&#8221; global_colors_info=&#8221;{}&#8221;][\/et_pb_image][et_pb_text _builder_version=&#8221;4.25.0&#8243; _module_preset=&#8221;default&#8221; text_text_color=&#8221;#002843&#8243; text_line_height=&#8221;1.2em&#8221; link_font=&#8221;||||on|||#8BCE33|&#8221; link_text_color=&#8221;#002843&#8243; header_4_font=&#8221;||||||||&#8221; header_4_text_color=&#8221;#005167&#8243; header_4_font_size=&#8221;25px&#8221; header_4_line_height=&#8221;2em&#8221; custom_padding=&#8221;|20px|20px|20px|false|false&#8221; global_colors_info=&#8221;{}&#8221; link_text_color__hover_enabled=&#8221;on|desktop&#8221; link_text_color__hover=&#8221;#6EC200&#8243;]<\/p>\n<h4>Dr. Kozma-Bogn\u00e1r L\u00e1szl\u00f3<\/h4>\n<p><strong>egyetemi docens, csoportvezet\u0151<\/strong><\/p>\n<p><span style=\"font-family: 'ETmodules';\">\ue090 <\/span><a href=\"tel:+3662544269\">54-4269<\/a><\/p>\n<p><span style=\"font-family: 'ETmodules';\">\ue076 <\/span><a href=\"&#x6d;&#97;i&#x6c;&#116;o&#x3a;&#x6b;&#111;&#x7a;&#x6d;&#97;-&#x62;&#111;g&#x6e;&#x61;&#114;&#x2e;&#x6c;&#97;s&#x7a;&#108;o&#x40;&#x73;&#122;&#x74;&#x65;&#46;h&#x75;\">&#x6b;&#x6f;&#x7a;&#109;&#97;-b&#x6f;&#x67;&#x6e;&#97;&#114;&#46;l&#x61;&#x73;&#x7a;&#108;&#111;&#64;s&#x7a;&#x74;&#x65;&#46;&#104;u<\/a><\/p>\n<p>MTMT: 10012861\u00a0 \u00a0<a href=\"https:\/\/m2.mtmt.hu\/gui2\/?type=authors&amp;mode=browse&amp;sel=10012861&amp;view=dataSheet\" target=\"_blank\" rel=\"noopener\">MTMT adatlap<\/a><\/p>\n<p>[\/et_pb_text][\/et_pb_column][et_pb_column type=&#8221;1_3&#8243; _builder_version=&#8221;4.19.5&#8243; _module_preset=&#8221;default&#8221; box_shadow_style=&#8221;preset1&#8243; box_shadow_blur=&#8221;10px&#8221; global_colors_info=&#8221;{}&#8221;][et_pb_image src=&#8221;https:\/\/szte-genetika.hu\/wp-content\/uploads\/2026\/03\/Gyore_Nikolett_cut_jo-scaled.jpg&#8221; alt=&#8221;Ny\u00e1ri D\u00f3ra&#8221; title_text=&#8221;Gy\u00f6re_Nikolett&#8221; align_tablet=&#8221;&#8221; align_phone=&#8221;center&#8221; align_last_edited=&#8221;on|phone&#8221; _builder_version=&#8221;4.25.0&#8243; _module_preset=&#8221;default&#8221; width=&#8221;100%&#8221; width_tablet=&#8221;100%&#8221; width_phone=&#8221;100%&#8221; width_last_edited=&#8221;on|phone&#8221; custom_margin=&#8221;||10px||false|false&#8221; custom_padding=&#8221;20px|20px||20px|false|false&#8221; custom_padding_last_edited=&#8221;off|desktop&#8221; global_colors_info=&#8221;{}&#8221;][\/et_pb_image][et_pb_text _builder_version=&#8221;4.25.0&#8243; _module_preset=&#8221;default&#8221; text_text_color=&#8221;#002843&#8243; text_line_height=&#8221;1.2em&#8221; link_font=&#8221;||||on|||#8BCE33|&#8221; link_text_color=&#8221;#002843&#8243; header_4_font=&#8221;||||||||&#8221; header_4_text_color=&#8221;#005167&#8243; header_4_font_size=&#8221;25px&#8221; header_4_line_height=&#8221;2em&#8221; custom_padding=&#8221;|20px|20px|20px|false|false&#8221; global_colors_info=&#8221;{}&#8221; link_text_color__hover_enabled=&#8221;on|desktop&#8221; link_text_color__hover=&#8221;#6EC200&#8243;]<\/p>\n<h4>Gy\u00f6re Nikolett<\/h4>\n<p><strong>PhD hallgat\u00f3<\/strong><\/p>\n<p><span style=\"font-family: 'ETmodules';\">\ue076 <\/span><a href=\"&#x67;&#121;&#111;r&#x65;&#x2e;&#110;i&#x6b;&#x69;&#64;gm&#x61;&#105;&#108;&#46;&#x63;&#x6f;&#109;\">&#x67;&#121;o&#x72;&#x65;&#46;n&#x69;&#x6b;&#105;&#64;&#x67;&#109;a&#x69;&#x6c;&#46;c&#x6f;&#x6d;<\/a><\/p>\n<p>MTMT: 10101893 <a href=\"https:\/\/m2.mtmt.hu\/gui2\/?type=authors&amp;mode=browse&amp;sel=authors10101893\" target=\"_blank\" rel=\"noopener\">MTMT adatlap<\/a>[\/et_pb_text][\/et_pb_column][et_pb_column type=&#8221;1_3&#8243; _builder_version=&#8221;4.19.5&#8243; _module_preset=&#8221;default&#8221; box_shadow_style=&#8221;preset1&#8243; box_shadow_blur=&#8221;10px&#8221; global_colors_info=&#8221;{}&#8221;][et_pb_image src=&#8221;https:\/\/szte-genetika.hu\/wp-content\/uploads\/2023\/02\/DosztigMonika.webp&#8221; alt=&#8221;Dosztig M\u00f3nika&#8221; title_text=&#8221;Dosztig M\u00f3nika&#8221; align_tablet=&#8221;&#8221; align_phone=&#8221;center&#8221; align_last_edited=&#8221;on|phone&#8221; _builder_version=&#8221;4.19.5&#8243; _module_preset=&#8221;default&#8221; width=&#8221;100%&#8221; width_tablet=&#8221;100%&#8221; width_phone=&#8221;100%&#8221; width_last_edited=&#8221;on|phone&#8221; custom_margin=&#8221;||10px||false|false&#8221; custom_padding=&#8221;20px|20px||20px|false|false&#8221; custom_padding_last_edited=&#8221;off|desktop&#8221; global_colors_info=&#8221;{}&#8221;][\/et_pb_image][et_pb_text _builder_version=&#8221;4.19.5&#8243; _module_preset=&#8221;default&#8221; text_text_color=&#8221;#002843&#8243; text_line_height=&#8221;1.2em&#8221; link_font=&#8221;||||on|||#8BCE33|&#8221; link_text_color=&#8221;#002843&#8243; header_4_font=&#8221;||||||||&#8221; header_4_text_color=&#8221;#005167&#8243; header_4_font_size=&#8221;25px&#8221; header_4_line_height=&#8221;2em&#8221; custom_padding=&#8221;|20px|20px|20px|false|false&#8221; global_colors_info=&#8221;{}&#8221; link_text_color__hover_enabled=&#8221;on|desktop&#8221; link_text_color__hover=&#8221;#6EC200&#8243;]<\/p>\n<h4>Balogn\u00e9 Dosztig Monika<\/h4>\n<p><strong>technikai asszisztens<\/strong><\/p>\n<p><span style=\"font-family: 'ETmodules';\">\ue090 <\/span><a href=\"tel:+3662544268\">54-4268\u00a0<\/a><\/p>\n<p><span style=\"font-family: 'ETmodules';\">\ue076 <\/span><a href=\"&#109;a&#x69;l&#x74;o&#x3a;b&#x61;l&#x6f;g&#x6e;&#101;&#x2e;&#100;&#x6f;&#115;&#x7a;&#116;&#x69;&#103;&#x2e;&#109;&#x6f;&#110;i&#x6b;a&#x40;s&#x7a;t&#x65;&#46;&#x68;u\">&#98;&#x61;&#108;&#x6f;&#103;&#x6e;&#101;&#x2e;&#100;&#x6f;&#115;&#x7a;t&#x69;g&#x2e;m&#x6f;n&#x69;k&#x61;&#64;&#115;&#x7a;&#116;&#x65;&#46;&#x68;&#117;<\/a><\/p>\n<p>[\/et_pb_text][\/et_pb_column][\/et_pb_row][\/et_pb_section]<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Kronogenetikai kutat\u00f3csoportKutat\u00e1si t\u00e9ma Az eukari\u00f3ta cirkadi\u00e1n \u00f3r\u00e1k val\u00f3j\u00e1ban oszcill\u00e1l\u00f3 g\u00e9nh\u00e1l\u00f3zatok, amelyekben az els\u0151dleges ritmus az \u00f3rag\u00e9nek transzkripci\u00f3j\u00e1nak szintj\u00e9n alakul ki, majd t\u00f6bb kieg\u00e9sz\u00edt\u0151 szab\u00e1lyoz\u00f3 mechanizmus k\u00f6zrem\u0171k\u00f6d\u00e9s\u00e9vel \u00e1ll\u00edt\u00f3dik kb. 24 \u00f3r\u00e1s peri\u00f3dusra (1. \u00e1bra). Ez az alap-oszill\u00e1ci\u00f3, mint egyfajta karmester, sz\u00e1mos \u00e9letfolyamat megjelen\u00e9s\u00e9t szab\u00e1lyozza olyan m\u00f3don, hogy azok az arra legmegfelel\u0151bb napszakban t\u00f6rt\u00e9njenek. Bel\u00e1that\u00f3, hogy az [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_et_pb_use_builder":"on","_et_pb_old_content":"","_et_gb_content_width":"","footnotes":""},"class_list":["post-170","page","type-page","status-publish","hentry"],"_links":{"self":[{"href":"https:\/\/szte-genetika.hu\/en\/wp-json\/wp\/v2\/pages\/170","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/szte-genetika.hu\/en\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/szte-genetika.hu\/en\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/szte-genetika.hu\/en\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/szte-genetika.hu\/en\/wp-json\/wp\/v2\/comments?post=170"}],"version-history":[{"count":13,"href":"https:\/\/szte-genetika.hu\/en\/wp-json\/wp\/v2\/pages\/170\/revisions"}],"predecessor-version":[{"id":434,"href":"https:\/\/szte-genetika.hu\/en\/wp-json\/wp\/v2\/pages\/170\/revisions\/434"}],"wp:attachment":[{"href":"https:\/\/szte-genetika.hu\/en\/wp-json\/wp\/v2\/media?parent=170"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}